Why You Should Choose Folate (Not Folic Acid) for Fertility + Pregnancy
When it comes to preparing for pregnancy or supporting your body through it, one of the most essential nutrients is vitamin B9, Folate.. You’ve probably heard of it as folic acid, but here's the thing: folic acid is not the same as folate and that really matters.
Why it matters for Fertility and Pregnancy
Vitamin B9/Folate supports baby’s neural tube development
Folate is crucial in the first few weeks of pregnancy to help form your baby’s brain and spinal cord. Adequate folate reduces the risk of neural tube defects like spina bifida.
It also helps…
Prevent Miscarriage + Placental Issues
Healthy folate levels are linked to lower risks of early loss, preeclampsia, and placental abruption.
Supports DNA Synthesis & Egg Quality
Folate plays a key role in cell division and repair , which means it supports healthy egg maturation and embryo development.
MTHFR Gene Mutation Awareness
An estimated 40–60% of people have a genetic variation (MTHFR) that affects their ability to convert folic acid into active folate. For these individuals, taking folic acid can actually build up unmetabolized folic acid in the blood, potentially doing more harm than good.
Folic Acid vs Folate
Folic Acid
What it is: The synthetic version of B9 used in supplements and fortified foods.
Sources: Prenatal vitamins, cereals, enriched flour.
How your body uses it: Must be converted by the liver (via the MTHFR enzyme) into the active form (5-MTHF) before the body can use it.
Potential issues: Some people have a MTHFR gene mutation that reduces their ability to convert folic acid, which may lead to unmetabolized folic acid circulating in the blood (linked to inflammation, fertility issues, and more).
Folate aka Methylated Folate or 5-MTHF
What it is: The naturally occurring form of vitamin B9 found in food, and supplements. It looks like methylated folate or 5-MTHF on labels (active form of folate).
Sources: Leafy greens, liver, avocado, asparagus, citrus fruits, lentils.
How your body uses it: Folate is bioavailable (especially in its active form, 5-MTHF) and more easily processed by your body.
Best for: People with MTHFR gene variants
What to do:
If you're choosing a supplement (especially for fertility, pregnancy, or nervous system support), look for methylated folate or 5-MTHF , not folic acid in your supplements. Please do not buy your supplements from Amazon it is not regulated at all. It is always recommended to purchase quality supplements through any health care provider.
Questions? Send us an e-mail or schedule a free consultation with Dr. Hannah
Disclaimer: This content is for educational purposes only and is not intended as medical advice. Please consult with your doctor or qualified healthcare provider before starting any supplements or making changes to your health routine, especially during pregnancy.